A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising. A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.After the apes suffer unimaginable losses, Caesar wrestles with his darker instincts and begins his own mythic quest to avenge his kind. After the apes suffer unimaginable losses, Caesar wrestles with his darker instincts and begins his own mythic quest to avenge his kind.